naturalproducts相关论文
Natural products (NPs),especially those from traditional herbal medicines,can evidently modulate human gene expres-sion ......
目的 木果楝是一种红树林树木,其在多个亚洲国家作为药用植物被用于治疗多种疾病.已经从该植物中分离出许多具有生物活性的天然产......
Experimental and Computational Analysis of the Solution and Solid-State Conformations of Hexadepsipe
Chemical investigation of Beauveria felina,a marine-derived entomopathogenic fungus,obtained two new destruxin hexadepsi......
Chiral pools have been commonly utilized as inexpensive and versatile building blocks in organic synthesis.In this accou......
(±)-Atrachinenins A-C,Three Pairs of Caged C27 Meroterpenoids from the Rhizomes of Atractylodes chin
(+)-Atrachinenins A-C(1-3),three meroterpenoids possessing novel C27 skeletons,were isolated from the rhizomes of At-rac......
Tabernaesine J,a Novel Vincamine-Type Indole Alkaloid with 6/5/6/6/6/5/5 Heptacyclic-Ring System Sca
Tabernaesine J(1),an unprecedented vincamine-type indole alkaloid with 6/5/6/6/6/5/5 heptacyclic-ring system,as well as ......
Hybeanones A and B (1 and 2),two highly oxygenated and rearranged polycyclic polyprenylated acylphloroglucinols (PPAPs),......
Cisplatin is a clinically advanced and highly effective anticancer drug used in the treatment of a wide variety of malig......
Cyclic and Linear Thiopeptides from Soil-Derived Streptomyces sp.CPCC 203702 with Antiviral and Anti
A new cyclic thiopeptide,berninamycin F (3),three new linear thiopeptides,berninamycins G—I (4-6),and two known bernina......
Peniazaphilones A—I,Produced by Co-culturing of Mangrove Endophytic Fungi,Penicillium sclerotiorum T
Co-culturing the mangrove endophytic fungus Penicillium sclerotiorum THSH-4 with Penicillium sclerotiorum ZJHJJ-18 in PD......
The EtOAc fraction of Alpinia katsumadai seeds showed significant inhibition on glycogen phosphorylase a (GPa) with inhi......
Baicalin attenuates blood-spinal cord barrier disruption and apoptosis through PI3K/Akt signaling pa
Baicalin is a natural active ingredient isolated from Scutellariae Radix that can cross the blood-brain barrier and exhi......
Natural products are one of the important sources for the discovery of new drugs.Betulinic acid(BA),a pentacyclic triter......
Uncommon N-Methoxyindolediketopiperazines from Acrostalagmus luteoalbus,a Marine Algal Isolate of En
Four new N-methoxyindolediketopiperazines (acrozines D-G,1-4) and six known congeners (5-10) were purified from the orga......
Five novel pterocarpan derivatives (1-5) and three known pterocarpans were isolated from the roots of Sophoraflavescens ......
Lepithiohydimerins A-D:Four Pairs of Neuroprotective Thiohydantoin Dimers Bearing a Disulfide Bond f
An HPLC-UV-guided separation was performed and four pairs of unprecedented macathiohydantoin dimers,lepithiohydimerins A......
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Cangumycins A-F (1-6),six new angucyclinone analogues,together with two known ones (7 and 8),were isolated from the ferm......
Traditional Chinese Medicine (TCM) is an important reservoir for bioactive natural products.TCM extraction methods by wa......
Natural Products always exhibit more intellectual bioactivities and atom economy,and it\'s also an important source of......
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A novel sesquiterpenoid dimer,named multistalide C (1),together with two known congeners,shizukaols C (2) and D (3),was ......
Korean red ginseng to tackle Helicobacter-associated gastric cancer through either rejuvenating atro
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A luminescence-based cytotoxicity assay revealed 20-Deoxyingenol 3-angelate is a potent immunostimul
Objective As central effector lymphocytes of the innate immune system,natural killer(NK)cells can eliminate transformed ......
New challenges in analytical data analysis and management for pharmaceutical research and developmen
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Recently, the hydrophilic interaction chromatography (HILIC) developed rapidly for highly polar compounds with good sepa......
Characterization of broad range phosphopantetheinyl transferases for heterologous expression of natu
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Protective effect of natural products against doxorubicin-induced cardiotoxicity:A systematic review
Background: Doxorubicin(Dox),an anthracycline antibiotic,is one of the most potent and widely used chemotherapeutic agen......
AIM The goal of the study is to find compounds from natural products especially traditional Chinese medicines (TCM) that......
The biosynthetic cationic polyene cyclizations of acyclic precursors squalene and (3S)-2,3-oxidosqualene lead to a vast ......
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Screening of Jumonji domain-containing protein 3 inhibitors innatural products by capillary electrop
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Natural Products from Chinese Herbal Medicine for Drug Discovery:Proteome-wide Mapping of Interactom
Traditional Chinese Medicine(TCM,Zhong-Yi)has existed for thousands of years.A key component of TCM is Chinese Herbal Me......
Microbial genomes encode dramatic number of natural product biosynthetic gene clusters(BGCs),and the products of vast ma......
This presentation involved in the development and application of virtual screening methods to aid the design of bioactiv......
A method for screening of histone deacetylase(HDAC)inhibitors in natural products by using capillary electrophoresis(CE)......
Me2AlSEt-Promoted Domino Dieckmann Cyclization Enables the Total Synthesis of Polycyclic Polyprenyla
A bioinspired,Me2AlSEt-promoted domino Dieckmann cyclization was developed for the syntheses of nine polycyclic polypren......
Fluorescent ligand fishing combination with in-situ imaging to screen Hsp 90 inhibitors from natural
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Screening of mTOR Inhibitors in Natural Extracts by Capillary Electrophoresis in Combination with Hi
In this study,a reliable approach for identifying mammalian target of rapamycin inhibitors in natural extracts by using ......
Leucas zeylanica belongs to Leucas genus (Lamiaceae), which distributes in Baoting, Lingshui, Ledong, Dongfang, Changjia......
Main observation and conclusionrnSix new meroterpenoids,bipolarinoids A-F (1-6),and two known congeners (7-8) were isola......
Main observation and conclusionrnBoswelliains A-E (1-5),five new cembrane-type diterpenoids,were isolated from the resin......
商陆是一种有名的传统草药,在中国已有数千年的历史。此外,商陆也在世界范围内用于不同的传统植物药物和顺势疗法制剂。本文对商陆......
Candida is an intractable life-threatening pathogen.Candida infection is extremely difficult to eradicate,and thus is th......
